Not long ago, it waqsn't uncommon for us (my boys and I) to go out and kill 3 to 5 hogs in a day. BUT, now that they both have families of their own and are busy taking care of them we don't get out as often. A boiler room shot on hogs is the bets course. YES, you can loose some meat BUT, that just means you can take another one to make up for it. REMEMBER, they have a "sheild" of gristle from just behind each ear down to the back edge of the shoulder that CAN and HAS stopped high powered rifle bullets in the past. IF you are a person who learns from the past, you'll remember this fact.
THAT being said, a shot placed in the heaert and lungs is STILL the best shot to take. Take your time and stalk up on them. They can smell and hear as well as or better than a deer BUT, they can not see even 1/2 as good. cent control and camo is the key. The noise factor is not a major factor IF you consider the noise they make as they feed, turning leaves and brush and all the debris on the foest floor to find a meal. Just move ONLY when they are feeding. Stalk up on them to with in 50 to 75 yards and even the largest hog will fall to a bullet placed in the shoulder, through the lungs/spine or heart and with todays modern ammunition and calibers penetration through the sheild is a minor consideration but still a consideration. Look for the oppertunity of a shot while the closest foreleg is forward or the animal is angling (quartering) SLIGHTLY away. Take your time, place the shot and be patient afterwards. Give the animal a chance to settle and die before you start tracking. Hogs are about 1/2 bulldozer, so keep your eyes, ears and nose open as you trach. Have your weapon loaded and ready for a follow up shot should the need arise. ALWAYS have an escape plan should you come upon the hog wounded hog who has not expired yet. As simple as it sounds, even a decent tree to keep between you and the hog.
IF you take your time, use your common sense and PLACE the bullet where it needs to be. Your chances of bringing home the bacon are very good. Take your time and be safe and have fun.